Almost every question in this series has one product behind it: one tablet, one label, one answer. "Dewormer" is not like that. It is a job description printed on a box, and at least four different drugs are sold to do that job — with documented safety margins that differ by more than an order of magnitude, labels that disagree with each other about pregnancy, and one active ingredient that quietly turns into another one inside your dog.
Search the question at 11pm and every result tells you the same thing: dewormers have a wide safety margin, a double dose is unlikely to be a problem. That is true far more often than not. What none of those pages ask is the question that actually determines the answer — which drug is in the tube?
Key takeaways
- "Dewormer" is a job, not a drug. Fenbendazole, pyrantel pamoate, praziquantel and febantel are all sold under that word, and their labels answer this question differently — one is cleared for pregnant bitches, another says "DO NOT USE IN PREGNANT ANIMALS."¹³
- For the two commonest actives the margin is genuinely wide, and it is measured. The pyrantel label puts the acute oral LD50 in dogs above 314 mg base per lb, "which indicates a therapeutic index in excess of 138 times the recommended dosage."²
- Two doses is often the instruction. Safe-Guard is labelled at 50 mg/kg "for 3 days in a row," and CAPC recommends deworming puppies "every 2 weeks" until monthly prevention starts.¹⁶
- The real hazard is stacking two products, not repeating one. Febantel "is metabolized to the benzimidazoles fenbendazole and oxfendazole," so two boxes sharing no ingredient name can still deliver the same drug twice.⁴
Can I give my dog two doses of dewormer?
Not on your own initiative — but before you panic, find the packaging, because there is a real chance the second dose was the treatment working as designed. Unlike a monthly flea preventive or a once-daily tablet, several dewormers are labelled to be repeated within days, and the schedules differ enough that no single answer covers them.
The Merck Veterinary Manual sets the general expectation honestly: "Most anthelmintics have wide safety margins (ie, the dosage that can be given to an animal before adverse effects are induced is much higher than the recommended dosage)."⁵ For the benzimidazole family it even explains why — "the wide safety margin of benzimidazole anthelmintics is due to their greater selective affinity for parasitic beta tubulin than for mammalian beta tubulin."⁵ The drug is built to bind a structure your dog does not have much of.
But "most" is doing work in that sentence, and Merck immediately shows the contrast: for levamisole, "the safety index (SI... ) is not as wide... (SI = 4–6)."⁵ A four-fold margin and a hundred-and-thirty-eight-fold one are both, in Merck's sense, anthelmintics — which is precisely why "dewormers are safe" is too coarse a statement to act on. The useful first move is not reassurance; it is reading the ingredient line.
| Which situation are you in? | What it means | What to do |
|---|---|---|
| Two doses of a plain pyrantel pamoate liquid or tablet | The widest documented margin of the group — a stated therapeutic index above 138×, and 40× daily for up to 90 days produced no significant morphological abnormalities² | Call your clinic today for advice, but this is the most forgiving version |
| Two doses of fenbendazole granules on consecutive days | Very possibly not an error at all — the label directs 50 mg/kg once daily "for 3 days in a row"¹ | Check the label and the vet's instruction before assuming a mistake |
| Two different products given within a few days | The version that matters most. Febantel converts to fenbendazole in the body, and pyrantel appears in several product types⁴ | Call today, with both boxes, and read out every active ingredient |
| A doubled combination tablet containing febantel and praziquantel | Thinner reassurance. The label's tolerance study at 5× for 3 days produced vomiting, non-formed stools and raised liver enzymes³ | Call today. Say "febantel" on the phone |
| Your dog is pregnant, or may be | The labels split here. Safe-Guard is cleared for pregnant bitches; the febantel combination says "DO NOT USE IN PREGNANT ANIMALS"¹³ | Call now and name the product exactly |
| Your dog was already unwell before the dose | The Safe-Guard label's own precaution: "Do not deworm a dog or puppy that is sick."¹ | Call today and describe what was wrong beforehand |
From the FDA-approved labels for Safe-Guard Canine, Nemex-2 and Drontal Plus via DailyMed, and the Merck Veterinary Manual. The rows differ in how fast you dial, not whether.
Which dewormer is actually in your dog?
One of four drugs, most likely, and the box will tell you in a line most people never read. Each targets a different set of parasites, which is why the products are not interchangeable and why owners so often end up giving two of them.
Fenbendazole is the granule you sprinkle on food — Safe-Guard Canine and Panacur C. Its label lists tapeworms (Taenia pisiformis), roundworms, hookworms and whipworms, and it is dosed at 50 mg/kg (22.7 mg/lb) daily, repeated for three days.¹ Pyrantel pamoate is the liquid wormer for puppies — Nemex-2 and its many store-brand equivalents, at 4.54 mg of pyrantel base per mL, one teaspoon per 10 lb.² VCA describes it as treating "intestinal roundworm, hookworm, and stomach worm parasites," acting "within one to two hours."⁷ Note the gap: no tapeworms.
Praziquantel is what fills that gap, and the difference is narrower than "tapeworms or not" suggests. The fenbendazole label covers exactly one tapeworm, Taenia pisiformis.¹ The pyrantel label covers none.² The praziquantel-containing tablets add Dipylidium caninum — the flea tapeworm, the one most dogs actually get — plus Echinococcus granulosus and control of E. multilocularis.³ That is why "it says tapeworms on the box" is not the same claim on two different boxes. And febantel, the third active in those tablets, is the one worth knowing about, because it is the reason two dissimilar boxes can hold the same drug.
There is a fifth thing owners call a dewormer, and it belongs in a different conversation: the monthly broad-spectrum preventive, whose worm cover rides along with a macrocyclic lactone such as ivermectin or milbemycin. Those products are dosed monthly, not in courses, and they carry a breed consideration the intestinal wormers do not — in its discussion of dogs susceptible to ivermectin toxicity, Merck records that "a defect in the gene for P-glycoprotein has been identified in these dogs and also in some Australian Shepherds, English Shepherds, and Shetland Sheepdogs," adding that "genetic testing is now available to identify individual dogs susceptible to ivermectin toxicity."⁵ If the box you doubled was a monthly chew rather than a worming course, that is a different incident with a different answer — start with the heartworm preventive guide instead, and say the breed on the phone.
That dashed arrow is the practical point of this whole article. Febantel, as the 2025 case report below puts it, "is metabolized to the benzimidazoles fenbendazole and oxfendazole."⁴ A dog who gets a Safe-Guard course from the vet and a three-way tablet from the pet shop has had the same benzimidazole twice, and nothing on either carton says so.
How much room does the label actually leave?
More than most owners expect, and the numbers are printed on the labels rather than left to reassurance. This is the part the forum answers get broadly right and never source.
Pyrantel is the standout. Nemex-2's label reports that "the acute oral LD50 of pyrantel pamoate administered in gelatin capsules to female and male dogs is greater than 314 mg base per lb of body weight, which indicates a therapeutic index in excess of 138 times the recommended dosage."² The chronic data is in the same direction: "no significant morphological abnormalities could be attributed to Nemex-2 when administered to dogs at daily dose rates up to 94 mg base per lb of body weight (40x) for periods of 19, 30, and 90 days," in studies that "included nursing pups, weaned pups, adults, pregnant bitches, and males at stud."² Against that, one extra teaspoon is a rounding error.
Sources: FDA-approved labels via DailyMed for Safe-Guard Canine (fenbendazole), Nemex-2 (pyrantel pamoate) and Drontal Plus. These are different products with different endpoints — a vomiting rate, a tolerance study and an LD50-derived index — plotted on one axis for scale only, not as a single comparable safety curve. The 138× figure is an index calculated from an acute lethal dose, not a dose anyone has tested as safe.
Fenbendazole sits in the same comfortable territory at the ordinary dose: its label records that "in U.S. clinical studies 3 of 240 dogs (about 1% of the treated dogs) had vomiting associated with the use of the product."¹ That is the baseline at the correct dose — worth remembering when a dog vomits after a doubled one, because it does not automatically mean the extra dose caused it.
Where does that reassurance stop?
At the combination tablets, and specifically at febantel — where there is now a published canine case that the blanket "wide safety margin" line does not cover. It is worth reading carefully, because it is easy to over-read.
In 2025, Frontiers in Veterinary Science published what the authors call "the first report of suspected bone marrow toxicity secondary to febantel administration." A 6-year-old, 35.6 kg neutered male Labrador Retriever was prescribed a three-way tablet for presumptive giardiasis and given the proper dosage for his weight — 1.5 tablets delivering 28.6 mg/kg of febantel, "orally once daily for 5 days." Fifteen days after the course, he presented for lethargy and fever with severe leukopenia (white cell count 0.3 k/µL against a reference interval of 5.6–15.1) and thrombocytopenia. "Pancytopenia was noted, and bone marrow sampling was consistent with hypoplasia suspected to be due to the febantel administration as no other toxic insults were identified." He "made a full recovery in approximately 2 weeks after stopping the febantel."⁴
Three things about that case matter, and the third is the one to hold onto. First, it was a correct dose — which is precisely why "the margin is wide" is not the same statement as "there is no ceiling." Second, the mechanism is not mysterious: the authors note that "fenbendazole is another benzimidazole anthelminthic that has been shown to cause bone marrow hypoplasia and bone marrow necrosis in various species," and febantel becomes fenbendazole.⁴ Third — the honest scoping — it is a single case report, described as suspected, following five consecutive days of dosing, and the dog recovered fully. It is not evidence that one accidental extra tablet causes pancytopenia, and nobody should read it that way. What it justifies is treating a doubled febantel tablet as a same-day phone call rather than a shrug.
The labels draw a second line here. The three-way tablet's own tolerance testing found vomiting and non-formed stools at five times the labelled dose for three days, with elevated liver enzymes in some dogs that resolved within seven days.³ And its contraindication is the opposite of the granule's: "DO NOT USE IN PREGNANT ANIMALS. Dogs treated with elevated levels... of the combination of febantel and praziquantel in early pregnancy demonstrated an increased incidence of abortion and fetal abnormalities."³ Safe-Guard, meanwhile, "is safe for use in puppies 6 weeks or older and adult dogs, including pregnant bitches."¹ One word on the front, opposite instructions inside.
Was two doses actually the instruction?
Very often, yes — and this is the commonest reason people arrive at this question by mistake. Deworming is one of the few treatments in the cabinet where repeating within days is the design rather than the error.
The Safe-Guard label is explicit that the daily dose is "repeated... for 3 days in a row."¹ Nemex-2's puppy schedule lists treatment "at 2, 3, 4, 6, 8, and 10 weeks of age."² The Companion Animal Parasite Council goes further: "puppies should be given anthelmintics starting at 2 weeks of age and repeating every 2 weeks until regular broad-spectrum parasite control begins," and "all pups should be routinely treated with pyrantel pamoate at 2, 4, 6, and 8 weeks of age and then placed on a monthly preventive."⁶
The repetition is not caution — it is biology, and CAPC spells the reason out. Puppies are frequently infected before birth: "transplacental transmission of larvae from the bitch to the fetal pups in utero is an important route of infection for T. canis," and "many of the T. canis larvae ingested by adult dogs become arrested in somatic tissues," where they can be "activated to resume migration late in pregnancy."⁶ A dose clears what is in the gut on the day you give it; larvae still in tissue arrive afterwards. That is why one treatment is not a cure and why the interval is fixed rather than negotiable.
CAPC also explains why the schedule is worth getting right for reasons beyond the dog: "Toxocara spp. are well-documented and important zoonotic disease agents," infection "is most common in children," and larvated eggs "are commonly found in soil collected from playgrounds or parks, and the eggs survive and remain infective for many years."⁶
So before you treat this as an incident, check the label and the discharge notes. A second dose 24 hours after the first may be exactly what your vet asked for.
What should you do in the first hour?
Find the packaging, work out how much of which drug went in, and call — in that order. Have five things ready before you dial:
- The full product name and the active-ingredient line. "Dewormer" is not an answer to the question your vet will ask.
- Whether it was one product twice, or two products. Two different boxes is the more important version of this incident, not the less.
- Your dog's weight, and the weight band on the pack. Combination tablets come in fixed strengths — 22.7, 68.0 and 136.0 mg of praziquantel, with matched pyrantel and febantel — so a tablet sized for a large dog given to a small one is an arithmetic error, not a counting one.³
- How long ago, and whether anything has been eaten since.
- Whether your dog is pregnant, very young, or was unwell beforehand. All three appear as explicit label restrictions.¹³
If you cannot reach your clinic, the ASPCA Animal Poison Control Center is "available 24/7, 365 days a year" on (888) 426-4435; a consultation fee may apply.⁸ Do not induce vomiting on your own initiative — that is a clinical decision, and for drugs with this kind of margin it is rarely the right one.
What should you watch for, and for how long?
The digestive tract for a day or two, and — only for the benzimidazole products, and only if a repeated course was involved — the dog's energy and gums over the following fortnight. The two windows are different lengths, which is the part owners are never told.
| What you are seeing | What it usually is | How fast to act |
|---|---|---|
| One episode of vomiting, or looser stools, within a day | The expected reaction, and it happens at normal doses too — about 1% of dogs on the labelled fenbendazole course¹ | Watch. Keep water available and call if it continues past a day |
| Nausea, poor appetite or diarrhoea⁷ | VCA's listed side effects for pyrantel pamoate — uncommon and usually mild⁷ | Call today if it persists or your dog is a young puppy |
| Visible worms in the stool over the next few days | Expected after an effective treatment, not a sign of overdose — Nemex-2 is 85–99% efficacious against the four common intestinal species² | No action for the dose. Clean up promptly — the eggs are a human health matter⁶ |
| Repeated vomiting, or a dog who is flat and off food beyond 24 hours | Beyond the expected range for any of these drugs at a doubled dose | Call today, with the packaging |
| Lethargy, fever, pale gums or unexplained bruising in the following two weeks, after a repeated benzimidazole or febantel course⁴ | The presentation in the 2025 febantel case report — rare, and reported once, but it appeared 15 days after dosing⁴ | Go in. Ask for a complete blood count and name the product |
Signs as listed on the FDA-approved labels for Safe-Guard Canine and Nemex-2, VCA Animal Hospitals' pyrantel pamoate handout, and Petronzio et al. (2025). The last row describes a single published case following five days of dosing, not an expected outcome of one extra dose. A guide to urgency, not a diagnosis — describe what you are seeing to a veterinarian rather than matching it to a row yourself.
One more caution belongs here, and it is about routine rather than accidents. VCA notes that "pyrantel pamoate can be toxic when given regularly over a period of months."⁷ The margin on a single doubled dose is wide; the margin on a habit of extra doses is not the same thing.
How do you stop this happening again?
By writing down the product, not just the dose — because with dewormers the question "did someone already do it?" is the less useful half. What matters is which one they gave.
This category is unusually easy to double, for structural reasons. Treatment is intermittent rather than daily, so nothing in a pill organiser shows a gap. The products arrive from three different places — the vet, the pet shop, the breeder's going-home pack — and none of them knows what the others gave. And the packaging invites the mistake: four drugs, one word on the front, ingredient lines in small print on the back. A household where one person bought a liquid wormer and another gave the tablet from the vet has not been careless; it has been handed a system with no shared record.
The fix is a note made at the moment of dosing — date, product name in full, active ingredient, who gave it — visible to everyone before anyone reaches for a second box. That is the failure described in why pets miss their medication doses, running in reverse, and the systems in how to avoid double dosing your pet's medication apply directly. One addition here: if your dog is on a monthly combination preventive, check what is in it first, because pyrantel turns up as a second active in some heartworm chews as well as in the liquid wormer on the shelf — the same overlap problem, one shelf over.
Veterinary medical disclaimer: SteadyTails is a logging and coordination tool, not a substitute for veterinary care. Nothing here is a dosing instruction. "Dewormer" describes several different drugs with different labels, different contraindications and different safety margins, and the right response to an extra dose depends on your dog, the exact product given and what else has been given recently — only your veterinarian can tell you what to do and when the next dose is due. Never repeat or combine worming products on your own initiative, and never induce vomiting without being told to. If your dog vomits repeatedly, becomes lethargic or feverish, develops pale gums or unexplained bruising, or was pregnant or unwell when dosed, contact your veterinarian or an emergency animal hospital immediately. The ASPCA Animal Poison Control Center is available on (888) 426-4435, 24/7, 365 days a year; a consultation fee may apply.⁸
The dose nobody logs is the dose somebody repeats
Worming happens a few times a year, from three different sources, and leaves nothing behind but an empty packet. SteadyTails records every dose with the product name, the active ingredient, a timestamp and the name of whoever gave it, on one timeline the whole household can see — so the next person reaching for a box can check in three seconds instead of guessing. Coming soon to iOS and Android.
Join the SteadyTails waitlist →References
- DailyMed (U.S. National Library of Medicine), FDA-approved animal drug label. Safe-Guard® (fenbendazole) Canine Dewormer, Intervet Inc./Merck Animal Health. Composition: "Fenbendazole Granules 22.2% (222 mg/g)". Indications: "Tapeworms (Taenia pisiformis), Roundworms (Toxocara canis, Toxascaris leonina), Hookworms (Ancylostoma caninum, Uncinaria stenocephala), Whipworms (Trichuris vulpis)". Dosage: "The daily dose for Safe-Guard® Canine is 50 mg/kg (22.7 mg/lb) of body weight", with treatment repeated "for 3 days in a row". Safety: "Safe-Guard® Canine is safe for use in puppies 6 weeks or older and adult dogs, including pregnant bitches." Adverse reactions: "In U.S. clinical studies 3 of 240 dogs (about 1% of the treated dogs) had vomiting associated with the use of the product." Precaution: "Do not deworm a dog or puppy that is sick." dailymed.nlm.nih.gov Retrieved 2026-09-03.
- DailyMed (U.S. National Library of Medicine), FDA-approved animal drug label. Nemex®-2 (pyrantel pamoate) Suspension, Zoetis. Composition: "Each mL contains 4.54 mg of pyrantel base as pyrantel pamoate." Dosage: "Administer 1 teaspoon (5 mL) for each 10 lb of body weight"; puppy treatment "at 2, 3, 4, 6, 8, and 10 weeks of age". Efficacy: "Critical (worm count) studies in dogs demonstrated that Nemex-2 at the recommended dosage is highly efficacious against T. leonina (99%), T. canis (85%), A. caninum (97%), and U. stenocephala (94%)." Safety: "The acute oral LD50 of pyrantel pamoate administered in gelatin capsules to female and male dogs is greater than 314 mg base per lb of body weight, which indicates a therapeutic index in excess of 138 times the recommended dosage"; "no significant morphological abnormalities could be attributed to Nemex-2 when administered to dogs at daily dose rates up to 94 mg base per lb of body weight (40x) for periods of 19, 30, and 90 days"; the clinical studies "included nursing pups, weaned pups, adults, pregnant bitches, and males at stud" and "showed no drug-induced toxic effects". dailymed.nlm.nih.gov Retrieved 2026-09-03.
- DailyMed (U.S. National Library of Medicine), FDA-approved animal drug label. Drontal® Plus (praziquantel/pyrantel pamoate/febantel) Broad Spectrum Anthelmintic Tablets for Dogs, Elanco. Tablet strengths: "22.7 mg praziquantel, 22.7 mg pyrantel base as pyrantel pamoate and 113.4 mg febantel"; "68.0 mg praziquantel, 68.0 mg pyrantel base as pyrantel pamoate and 340.2 mg febantel"; "136.0 mg praziquantel, 136.0 mg pyrantel base as pyrantel pamoate, and 680.4 mg febantel". Indications: removal of tapeworms (Dipylidium caninum, Taenia pisiformis, Echinococcus granulosus, and removal and control of Echinococcus multilocularis), hookworms, ascarids and whipworms in dogs. Contraindications and warnings: "DO NOT USE IN PREGNANT ANIMALS. Dogs treated with elevated levels... of the combination of febantel and praziquantel in early pregnancy demonstrated an increased incidence of abortion and fetal abnormalities"; "NOT FOR USE IN PUPPIES LESS THAN 3 WEEKS OF AGE OR DOGS WEIGHING LESS THAN 2 LBS."; "KEEP OUT OF REACH OF CHILDREN". High-dose tolerance testing recorded vomiting and non-formed stools at five times the labelled dose for three days, with elevated liver enzymes in some dogs resolving within seven days. dailymed.nlm.nih.gov Retrieved 2026-09-03.
- Petronzio A, Carabetta D, Koid A. Bone marrow toxicity associated with febantel administration in a dog: Case Report. Frontiers in Veterinary Science, 2025. "The objective of this case report is to describe a case of bone marrow suppression suspected to be secondary to febantel administration in a dog. A 6-year-old neutered male Labrador Retriever was presented for lethargy and fever 15 days after receiving oral febantel. Pancytopenia was noted, and bone marrow sampling was consistent with hypoplasia suspected to be due to the febantel administration as no other toxic insults were identified. The dog made a full recovery in approximately 2 weeks after stopping the febantel." The dog was "a 6-year-old, 35.6 kg, neutered male Labrador Retriever" prescribed "Drontal Plus® for dogs 45 lbs. and greater" at "the proper dosage for presumptive giardiasis", where "1.5 tablets contain 5.7 mg/kg of praziquantel, 5.7 mg/kg of pyrantel pamoate, and 28.6 mg/kg of febantel total", given "orally once daily for 5 days". Initial findings included "severe leukopenia (white cell count of 0.3 k/uL; reference interval (RI): 5.6–15.1 k/uL), thrombocytopenia (39 k/uL automated count... RI: 161–513 k/uL)", progressing to "non-regenerative anemia (32.9%; RI: 39.9–58.2%)". The authors state that "febantel is metabolized to the benzimidazoles fenbendazole and oxfendazole, as shown in vitro studies and in vivo in cattle", that "fenbendazole is another benzimidazole anthelminthic that has been shown to cause bone marrow hypoplasia and bone marrow necrosis in various species", and that this is "the first report of suspected bone marrow toxicity secondary to febantel administration". frontiersin.org Retrieved 2026-09-03.
- Merck Veterinary Manual. Safety of Anthelmintics in Animals — "Most anthelmintics have wide safety margins (ie, the dosage that can be given to an animal before adverse effects are induced is much higher than the recommended dosage)"; "The wide safety margin of benzimidazole anthelmintics is due to their greater selective affinity for parasitic beta tubulin than for mammalian beta tubulin"; "Compared with that of benzimidazole, the safety index (SI; the ratio of the highest exposure to a drug that does not induce toxicity to the exposure that exerts efficacy) is not as wide for levamisole (SI = 4–6)"; "Administration of some benzimidazoles (eg, albendazole) is contraindicated in early pregnancy, particularly in sheep"; on macrocyclic lactone sensitivity, "a defect in the gene for P-glycoprotein has been identified in these dogs and also in some Australian Shepherds, English Shepherds, and Shetland Sheepdogs", and "genetic testing is now available to identify individual dogs susceptible to ivermectin toxicity". merckvetmanual.com Retrieved 2026-09-03.
- Companion Animal Parasite Council (CAPC). Ascarid (Toxocara canis, Toxocara cati, Toxascaris leonina) guideline — "Puppies should be given anthelmintics starting at 2 weeks of age and repeating every 2 weeks until regular broad-spectrum parasite control begins"; "all pups should be routinely treated with pyrantel pamoate at 2, 4, 6, and 8 weeks of age and then placed on a monthly preventive"; "kittens should be routinely treated with pyrantel pamoate beginning at 2 weeks of age and then placed on an appropriate monthly preventive"; "adult pets should receive year-round broad-spectrum parasite control with efficacy against ascarids". On why repeat treatments are required: "Transplacental transmission of larvae from the bitch to the fetal pups in utero is an important route of infection for T. canis"; "Many of the T. canis larvae ingested by adult dogs become arrested in somatic tissues"; "If arrested T. canis larvae are present in an intact female that becomes pregnant, the larvae are activated to resume migration late in pregnancy"; "Pups infected in utero will not shed eggs before 2.5 to 3 weeks of age". On zoonotic risk: "Toxocara spp. are well-documented and important zoonotic disease agents. Infection with Toxocara spp. is most common in children"; "Larvated eggs of Toxocara spp. are commonly found in soil collected from playgrounds or parks, and the eggs survive and remain infective for many years." capcvet.org Retrieved 2026-09-03.
- VCA Animal Hospitals. Pyrantel Pamoate — "It is used to treat intestinal roundworm, hookworm, and stomach worm parasites in many species, including dogs, cats, small mammals, and birds"; "this medication should take effect within one to two hours"; side effects "may include: Nausea, Vomiting, Lack of appetite, Diarrhea"; missed dose: "If you miss a dose, give it as soon as you remember, and then wait the recommended time for the next dose"; "Pyrantel pamoate can be toxic when given regularly over a period of months. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately." vcahospitals.com Retrieved 2026-09-03.
- ASPCA Animal Poison Control Center. Animal Poison Control — the centre's number is given as "(888) 426-4435"; "We are available 24/7, 365 days a year, so you can get expert guidance the moment a poisoning concern arises"; "A consultation fee may apply." aspca.org Retrieved 2026-09-03.